Gaucher disease
Gaucher disease (go-SHAY) is a rare inherited metabolic disorder in which a fatty substance called glucocerebroside builds up in the body’s cells. This buildup mainly affects the spleen, liver, and bones, leading to organ enlargement, bone disease, and blood problems. More than 90% of cases are Type 1, the non-neurological form. Gaucher disease is more common among people of Ashkenazi Jewish (Eastern and Central European Jewish) ancestry. Types of Gaucher Disease Type 1 (Non-neuropathic) – most common Symptoms vary widely and can appear in childhood, adolescence, or adulthood. Common features include: Enlarged spleen and liver Easy bruising or bleeding (low platelets) Abdominal pain or fullness Bone disease Bone pain Fragile bones and fractures Bone marrow problems causing anemia and fatigue Growth delays in children (short stature, delayed puberty) Lung involvement (less common), including breathing difficulties Type 2 (Acute neuropathic) – rare and severe Symptoms begin in infancy Rapid damage to the brain stem Affects breathing, swallowing, and muscle control Life expectancy is usually under 2 years Type 3 (Chronic neuropathic) Combines Type 1 symptoms with progressive neurological involvement Begins in childhood Symptoms may include: Abnormal eye movements Muscle spasms and seizures Loss of muscle control Dementia in adolescence or early adulthood Causes Gaucher disease is caused by a mutation in the gene responsible for producing an enzyme that breaks down glucocerebroside. Without enough of this enzyme, the fatty substance accumulates inside white blood cells (called Gaucher cells), which then damage tissues and organs. Inheritance Autosomal recessive A child must inherit two mutated genes (one from each parent) to develop the disease People with only one mutated gene are carriers and usually have no symptoms Risk Factors Ashkenazi Jewish ancestry (especially for Type 1) Family history of Gaucher disease Complications (mainly Type 1) Increased risk of Parkinson’s disease and Lewy body dementia Higher risk of blood and bone marrow cancers Worsening symptoms during pregnancy Increased risk of bleeding after childbirth Treatment & Monitoring There is no cure, but effective treatments are available: Enzyme replacement therapy (ERT) to break down the fatty substance Substrate reduction therapy (SRT) to limit its production Regular monitoring to assess organ size, bone health, and blood counts With early diagnosis and proper treatment, many people with Type 1 Gaucher disease can live full, active lives. If you or your child have symptoms suggestive of Gaucher disease, or if it runs in your family, genetic testing and specialist evaluation are recommended.
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PD Dr. med. Patrick Weber is a highly respected specialist in the implantation and revision of hip and knee endoprostheses. With extensive academic and surgical experience, he is recognized as one of Germany’s leading experts in modern joint replacement surgery. During his many years at the University Hospital of Munich (LMU) – Klinikum Großhadern, Dr. Weber served as Head of Hip Arthroplasty and Deputy Head of Knee Arthroplasty, gaining comprehensive expertise across the full spectrum of endoprosthetic surgery—including highly complex cases such as hip dysplasia and post-traumatic osteoarthritis. Expertise in Minimally Invasive Hip Replacement (AMIS) For many years, Dr. Weber has specialized in the minimally invasive, muscle-sparing implantation of hip prostheses using the AMIS method. He is internationally regarded as a reference surgeon and instructor for this advanced technique, which supports faster recovery and improved mobility. Another major focus of his work is the revision and replacement of existing hip and knee implants, particularly in cases of loosening, pain, or implant failure. Key Areas of Specialization Dr. Weber’s surgical expertise includes: Hip replacement surgery using the AMIS approach Knee replacement surgery, including unicondylar (partial) knee prostheses Implantation of hip and knee prostheses in complex anatomical situations, such as: Hip dysplasia Post-traumatic arthritis Revision arthroplasty (exchange of hip and knee prostheses) Conditions Treated Dr. Weber provides expert care for patients with: Coxarthrosis (hip osteoarthritis) Gonarthrosis (knee osteoarthritis) Painful or loosened endoprostheses Femoral head necrosis (avascular necrosis) Academic & International Recognition With more than 150 scientific publications and international lectures, PD Dr. Weber is a regularly invited speaker at leading national and global congresses focused on joint replacement and endoprosthetics. His combination of surgical precision, minimally invasive expertise, and academic leadership makes him a trusted authority in advanced hip and knee arthroplasty.

Director of the Hip Center – ATOS Clinic Munich The Hip Center at ATOS Clinic Munich is led by Dr. med. Raimund Völker, a founding member of the clinic and one of the most experienced specialists in hip endoprosthetics worldwide. Dr. Völker is among the very few internationally recognized surgeons who exclusively dedicate their practice to hip surgery. This exceptional level of specialization provides significant advantages for patients, allowing for highly precise treatment planning, advanced surgical expertise, and consistently outstanding outcomes. With over 20 years of experience in both standard hip replacement and bone-preserving hip resurfacing, Dr. Völker offers each patient the most suitable procedure based on individual anatomy, lifestyle, and long-term goals. Excellence in Hip Arthroplasty & Implant Quality Unlike standard approaches that rely on routine implants, Dr. Völker uses only high-quality, long-established original prosthetic systems at ATOS Clinic. This ensures: Maximum implant durability Long-term safety Excellent functional results His philosophy combines proven methods with innovation to provide the best possible joint replacement strategy for every patient. Minimally Invasive & Muscle-Sparing Surgery Dr. Völker applies modern surgical techniques that are: Minimally invasive Muscle-sparing Bone-conserving These approaches support faster recovery, improved mobility, and enhanced joint stability. Together with individualized implant selection and early intensive physiotherapy, patients benefit from an optimized Fast Track Recovery program. Key Areas of Expertise & Procedures Dr. Völker’s clinical focus includes: Diagnosis and treatment of hip osteoarthritis and its causes Advanced cartilage treatment options, including MRI-based cartilage cell therapy Total hip replacement (total endoprosthesis) Hip resurfacing surgery following the McMinn method (BHR) Short-stem hip prostheses Minimally invasive hip replacement techniques Enhanced Recovery Programs (ERP) Computer-assisted navigation for surgical precision

Specialist in orthopaedics and accident surgery, sports medicine Medical Director ATOS Clinic Munich Prof. Dr. med. Mark Tauber provides the entire spectrum of modern shoulder surgery. His main focus is on the minimally invasive treatment of upper arm head fractures and the arthroscopic treatment of shoulder pathologies Range of Services: Implantation and replacement of shoulder prostheses Arthroscopic suture of the rotator cuff Revisions after failed rotator cuff rupture Care of upper arm head fractures and long-term consequences Arthroscopic and open shoulder stabilisation after dislocation Dislocations of the shoulder joint Early osteoarthritis of the shoulder, cartilage regeneration Calculus shoulder Frozen shoulder
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