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Biliary Atresia Treatment in Children,
A-Medical - With more than 7 years of experience in the field of treatment in Turkey, treatment abroad and medical tourism, we serve those who want to receive treatment in Turkey and abroad!

What Is Biliary Atresia?


Biliary atresia is a rare but life-threatening condition affecting the bile ducts in infants. It is characterized by a blockage or absence of bile ducts, which prevents bile from draining from the liver to the small intestine. This results in bile accumulation within the liver, leading to inflammation, scarring, and eventual liver damage.


Unlike other congenital disorders, biliary atresia is not identifiable during pregnancy. It typically manifests a few weeks after birth, requiring prompt medical attention. Without treatment, this condition can cause cirrhosis and liver failure within months. The precise cause remains unknown, but early intervention is critical for improving outcomes.


Diagnosis And Tests


Diagnosing biliary atresia involves multiple steps, as its symptoms can mimic those of other liver or gastrointestinal disorders. The diagnostic process starts with a detailed medical history and physical examination, followed by specialized tests:


  • Blood Tests: These assess liver function by measuring levels of bilirubin, alkaline phosphatase, alanine transaminase (ALT), and aspartate transaminase (AST). Persistent elevation in conjugated bilirubin is a key indicator.

  • Ultrasound Imaging: Abdominal ultrasounds provide non-invasive visualization of the bile ducts and liver to detect abnormalities.

  • Hepatobiliary Scintigraphy (HIDA Scan): This test evaluates bile flow from the liver to the intestines using a radioactive dye.

  • Liver Biopsy: A small tissue sample is examined under a microscope to assess liver damage and identify characteristic fibrosis and bile duct proliferation.

  • Cholangiogram: Performed during surgery, this procedure involves injecting dye into the bile ducts to confirm a blockage.


Timely and accurate diagnosis is essential for effective treatment planning.


Symptoms And Causes


Biliary atresia presents with distinct symptoms, often appearing 2-8 weeks after birth. These symptoms include:


  • Jaundice: Persistent yellowing of the skin and eyes, caused by high bilirubin levels.

  • Acholic Stools: Pale or clay-colored stools due to lack of bile.

  • Dark Urine: A result of excess bilirubin being excreted by the kidneys.

  • Hepatomegaly: An enlarged liver detected during physical examination.

  • Poor Weight Gain: Malabsorption and nutritional deficiencies.


The exact cause of biliary atresia is unknown. Hypotheses suggest genetic predisposition, immune-mediated damage, or prenatal environmental factors. Certain cases may arise due to viral infections during pregnancy, but no definitive causative link has been established.


Biliary Atresia Treatment Options


Treatment for biliary atresia focuses on restoring bile flow and minimizing liver damage. The two primary approaches are surgical intervention and liver transplantation. These are supported by medical therapies to manage complications and improve overall health. The choice of treatment depends on the patient’s age, disease progression, and overall health condition.


Pediatric Biliary Atresia Treatment


In pediatric patients, treatment emphasizes early intervention to prevent irreversible liver damage. Multidisciplinary care is essential, involving pediatric surgeons, hepatologists, dietitians, and critical care teams. Early surgical correction offers the best chance of delaying or avoiding liver transplantation. Supportive care, such as vitamin supplementation and specialized nutrition plans, helps address malnutrition and fat-soluble vitamin deficiencies.


Biliary Atresia Surgery For Children


Surgical options aim to reestablish bile drainage, with the Kasai procedure being the primary treatment for biliary atresia. In cases where the Kasai procedure is unsuccessful or liver damage is extensive, liver transplantation becomes necessary.


Kasai Procedure For Biliary Atresia


The Kasai procedure, or hepatoportoenterostomy, is the first-line surgical intervention for biliary atresia. During this procedure, the blocked bile ducts are removed and replaced with a loop of the small intestine to create a pathway for bile drainage.


While the Kasai procedure can delay the need for a liver transplant, it is not a cure. Success rates vary based on factors such as age at surgery and the degree of liver damage. Infants undergoing this procedure before 2 months of age have the highest chances of success.


Potential complications of the Kasai procedure include cholangitis (bile duct infection), bile leakage, and progressive liver damage. Close monitoring and follow-up care are crucial to address these risks.


Liver Transplant For Biliary Atresia


A liver transplant is the definitive treatment for biliary atresia in children with advanced liver disease or those for whom the Kasai procedure fails. It involves replacing the diseased liver with a healthy donor liver, either from a deceased or living donor.


Advancements in surgical techniques and immunosuppressive therapies have significantly improved transplant outcomes. However, challenges such as organ shortages and the risk of post-transplant complications, including rejection and infection, remain.


Pre- and post-transplant care are critical to ensuring a successful outcome. This includes managing immunosuppressive medications, monitoring for complications, and providing psychosocial support for families.


Biliary Atresia Recovery In Children


Recovery after treatment depends on the intervention and the child’s overall health. Following the Kasai procedure, regular follow-up visits and monitoring of liver function are essential. Many children require long-term nutritional support and supplements to address malabsorption issues.

Post-liver transplant recovery involves extensive care to manage immunosuppression and prevent infections. Growth and developmental milestones should be closely monitored, as chronic liver disease can impact physical and cognitive development.

Biliary Atresia Symptoms And Treatment


Understanding the correlation between symptoms and treatment options is vital for timely intervention. Early recognition of symptoms such as jaundice, acholic stools, and hepatomegaly enables early diagnosis and increases the likelihood of successful treatment. The Kasai procedure is most effective when performed early, while liver transplantation remains the ultimate solution for end-stage liver disease.


Best Clinics for Biliary Atresia Treatment in Children


Biliary atresia is a rare and serious condition affecting the bile ducts in newborns. It requires expert care and often surgical intervention to manage effectively. For families seeking the best care for their children, accessing renowned clinics with specialized expertise is critical. Below is a comprehensive guide to some of the world’s best clinics offering treatment for biliary atresia in children.


List of the Best Liver Transplant Centres in the World including Cost and Success Rates

Hospital Country No. of Transplants Performed Liver Transplant Success Rate Cost of Liver Transplant (starting from) 
Apollo Hospitals India 4,300+ >90% USD 31,000 
Max Super Specialty Hospital India 2,600+ >95% USD 28,000 
Rainbow Children’s Hospital India 200+ >90% USD 25,000  
King’s College Hospital London Dubai UAE 300+ >95% USD 187,000 
Burjeel Hospital UAE 300+ >95% USD 123,000  
Memorial Hospital Turkey 350+ >93% USD 55,000  
Medipol University Hospital Turkey 400+ >95% USD 55,000 
Acibadem Hospital Turkey 500+ >94% USD 40,000 
Liv Hospital Turkey 1,000+ >90% USD 50,000  


Antalya Medical Park


Antalya Medical Park in Turkey stands out for its comprehensive pediatric gastroenterology and hepatology department. The clinic is renowned for its expertise in managing complex liver conditions like biliary atresia. The hospital boasts cutting-edge diagnostic tools, enabling early and accurate detection of bile duct abnormalities.




Surgeons at Antalya Medical Park specialize in the Kasai procedure, a critical surgery for biliary atresia that connects the liver to the small intestine. Additionally, the clinic’s pediatric liver transplantation program is one of the most advanced in the region, offering a lifeline for children with severe liver damage. Families can also expect holistic post-operative care, including nutritional counseling and regular monitoring of liver function.


ASAN Clinic


Located in South Korea, ASAN Clinic is globally recognized for its pioneering work in pediatric liver diseases. The hospital combines state-of-the-art medical technology with a team of leading hepatologists and pediatric surgeons. ASAN Clinic has a dedicated biliary atresia program focusing on both surgical and medical management.


The clinic’s innovative use of 3D imaging in surgical planning allows for precision in complex procedures like the Kasai portoenterostomy and liver transplants. Additionally, ASAN offers long-term follow-up care to monitor liver health and prevent complications such as infections or cirrhosis. Families seeking advanced, science-driven care often choose ASAN for its exceptional outcomes.


UAE Burjeel Clinic


Burjeel Clinic in the UAE is a center of excellence for pediatric hepatology and gastrointestinal conditions. The clinic offers a multidisciplinary approach to biliary atresia treatment, involving pediatric gastroenterologists, surgeons, and nutritionists. Burjeel Clinic’s commitment to family-centered care ensures parents are actively involved in every step of the treatment process.


Specialized services include minimally invasive surgical techniques that reduce recovery times and lower the risk of post-operative complications. The clinic is also equipped with advanced liver function monitoring systems, allowing for precise adjustments to treatment protocols.


LIV Hospital Istanbul


LIV Hospital in Istanbul is one of Turkey’s premier healthcare institutions, particularly for pediatric liver conditions. The hospital’s liver transplant program is internationally accredited, and its success rates for pediatric transplants are among the highest globally.


LIV Hospital’s biliary atresia team includes some of the country’s most experienced pediatric hepatologists and surgeons. The hospital uses advanced laparoscopic techniques for the Kasai procedure, which results in less scarring and faster recovery for children. Families can also benefit from LIV Hospital’s comprehensive rehabilitation services, ensuring a smooth recovery journey.


King's College Hospital Dubai


King's College Hospital in Dubai is an extension of the world-renowned King’s College Hospital in London, known for its expertise in liver and biliary diseases. The Dubai branch brings the same level of excellence to the Middle East, offering cutting-edge treatments for biliary atresia in children.

The hospital’s multidisciplinary approach includes pediatric hepatologists, interventional radiologists, and transplant surgeons. King’s College Hospital Dubai is especially adept at performing pediatric liver transplants, supported by an excellent pre- and post-operative care program. Parents often choose this hospital for its seamless integration of British medical standards and local accessibility.


Memorial Hospital (Turkey)


Memorial Hospital in Turkey is a leader in the treatment of pediatric liver conditions, including biliary atresia. The hospital is equipped with the latest medical technologies and offers a range of surgical and non-surgical treatments tailored to each child’s unique condition.


Memorial Hospital is particularly known for its advanced pediatric liver transplant program, which has saved the lives of numerous children with end-stage liver disease. The hospital’s dedication to research ensures that families receive the most up-to-date and effective treatment options available.


Centro Médico Teknon


Located in Barcelona, Spain, Centro Médico Teknon is renowned for its high-quality care and innovative treatments for pediatric liver diseases. The hospital’s pediatric surgery team is skilled in the Kasai procedure and other interventions for biliary atresia.


Centro Médico Teknon also offers comprehensive diagnostic services, including genetic testing to identify underlying factors contributing to biliary atresia. The hospital’s child-friendly environment and dedicated support staff ensure that young patients feel at ease throughout their treatment journey.


Madrid Quironsalud University Hospital


Madrid Quironsalud University Hospital is a prominent healthcare provider in Spain, specializing in pediatric hepatology and surgery. The hospital’s biliary atresia program integrates advanced imaging technologies for precise diagnosis and treatment planning.


The surgical team at Quironsalud is highly experienced in liver transplantation and other complex procedures. Families often choose this hospital for its holistic approach, which includes psychological support and counseling to help children and their families cope with the challenges of biliary atresia.


Hospital Quirónsalud Barcelona


Hospital Quirónsalud Barcelona is a leading medical institution in Spain, offering world-class care for pediatric liver diseases. The hospital’s biliary atresia team uses advanced laparoscopic techniques for surgical interventions, reducing recovery times and minimizing risks.


Quirónsalud Barcelona is also known for its robust follow-up care program, which includes regular liver function tests and nutritional assessments. The hospital’s commitment to continuous improvement ensures that families receive the best possible care.


Hospital Quironsalud Torrevieja


Hospital Quironsalud Torrevieja provides specialized care for children with biliary atresia, combining state-of-the-art technology with a compassionate approach. The hospital’s team of pediatric hepatologists and surgeons work closely to deliver personalized treatment plans.


Parents appreciate the hospital’s focus on minimally invasive techniques, which reduce pain and scarring for young patients. Quironsalud Torrevieja also offers excellent post-operative care, ensuring children achieve the best possible outcomes.


Hospital Sant Joan De Déu


Hospital Sant Joan De Déu in Barcelona is one of Europe’s foremost pediatric hospitals, offering comprehensive care for biliary atresia and other liver diseases. The hospital’s multidisciplinary team includes experts in pediatric hepatology, surgery, and transplantation.


Sant Joan De Déu is particularly noted for its expertise in pediatric liver transplants, with high success rates and excellent post-operative care. The hospital’s family-centered approach ensures that parents are supported throughout the treatment process.


Get Treatment for Biliary Atresia in Children Abroad with A-Medical


Navigating the complexities of international medical care can be daunting. A-Medical is a leading medical tourism company that simplifies this process for families seeking biliary atresia treatment abroad. With A-Medical, you can access world-class clinics, enjoy discounted treatment costs, and benefit from end-to-end support.


Key services include:


  • Coordinating with top clinics to secure appointments.

  • Managing travel and accommodation arrangements.

  • Providing language support and translation services.

  • Offering post-treatment follow-up care.


Families can rely on A-Medical to handle every detail, allowing them to focus on their child’s recovery. By choosing A-Medical, you gain access to the best medical expertise while ensuring a stress-free experience.


Mobile: (+994 10) 310 93 33

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